In 2018，two outbreaks of African swine fever（ASF）were identified in Henan Province. By rapid response，adopting quick operations and strict disposal measures，the outbreaks were effectively controlled. In this paper，major measures for ASF prevention and control in Henan were reviewed，such as registration of transport vehicles for live pigs，strengthening the building of cleaning and disinfecting service centers，intensifying supervision over scaled swine farms and breeding farms，strictly controlling the checkpoints and strengthening construction of animal disease control system and animal health supervision system. Meantime，the current problems were also put forward，including unimplemented bio-safety measures，difficulty in disposal of swill，unclear requirements for vehicle registration as well as potential risk factors in slaughterhouses. Then some suggestions were provided，such as，strengthening joint prevention and control among relevant organizations，cracking down illegal activities，intensifying bio-safety disposal measures and strengthening supervision over pig slaughtering，so as to provide some ideas for ASF prevention and control in China.