Since the outbreak of pneumonia caused by the novel coronavirus（2019-nCoV）in Wuhan City of Hubei Province in December 2019，it has spread in China and many other countries around the world，which is the focus of global attention. In order to clarify the relationship between 2019-nCoV and the known animal coronaviruses，the comprehensive analysis was performed to find the possible source of 2019-nCoV based on the host distribution，genetic phylogenetic analysis，host receptor analysis of coronaviruses in the study. The results showed that the genome homology between 2019-nCoV and the coronavirus RaTG13 detected from Rhinolophus affinis in Yunan Province was the highest（96.2%），and 2019-nCoV was closely related to RaTG13 in genetic phylogenetic analysis. The genetic relationship between 2019-nCoV and the two coronaviruses detected from seized smuggling pangolin in Guangdong and Guangxi were relatively longer compared with RaTG13，and the genome homology of the 2019-nCoV with coronaviruses detected from seized smuggling pangolin in Guangdong and Guangxi was 90.4% and 85.5%，respectively. Genetic distance between 2019-nCoV and coronaviruses obtained from known domestic livestock，poultry，pets including dogs and cats was genetically long，and the genome homology of 2019-nCoV with them was≤54.2%. Combined with the published surveillance results，the possibility of 2019-ncov originating from the known coronaviruses of domestic livestock，poultry，pets including dogs and cats is basically excluded.