上海市门诊宠物猫和动物园流浪猫的猫疱疹病毒1型中和抗体检测
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上海市科技兴农重点攻关项目(沪农科创字﹝2019﹞第3-3号);上海市农业领军人才项目


Detection of Neutralizing Antibodies against Feline Herpesvirus Type 1 in Stray Cats in Zoos and Clinical Pet Cats in Shanghai City
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    摘要:

    为了解临床中猫疱疹病毒1型(FHV-1)疫苗的免疫效果和流浪猫的FHV-1感染状况,利用临床分离株建立了FHV-1中和抗体检测方法,并对20份宠物门诊FHV-1免疫猫血清和10份未免疫的动物园流浪猫血清进行中和抗体检测。结果显示,免疫宠物猫和未免疫流浪猫的抗体阳性率均为60%。结果表明,上海市FHV-1疫苗免疫效果不佳,未免疫流浪猫FHV-1感染较严重。结果提示,需加强猫科动物的FHV-1免疫抗体监测,及时补免,同时加强流浪猫的管理、收容、免疫和监测。本研究为防控猫科动物FHV-1感染提供了参考。

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    In order to make clear the immune effect of feline herpesvirus type 1(FHV-1)vaccines and the status of infection with FHV-1 in stray cats,a detection method for neutralizing antibody against FHV-1 was established by the clinical isolates,and 20 serum samples from clinical pet cats with vaccination against FHV-1 and 10 serum samples from stray cats without vaccination in zoos were detected for neutralizing antibody. The results showed that the qualified rates of antibodies were both 60% in the two kinds of cats,which indicated that the immune effect was poor,and FHV-1 infection of stray cats without vaccination was serious. Therefore,surveillance for the antibodies against FHV-1 should be strengthened with timely supplement of vaccination,meanwhile,stray cats should be controlled,sheltered,vaccinated and monitored. Some references were consequently provided for prevention and control of FHV-1.

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赵洪进,白艺兰,杨显超,朱九超,卢军,陶田谷晟,于讳茹,葛杰,刘健,鞠厚斌,王建.上海市门诊宠物猫和动物园流浪猫的猫疱疹病毒1型中和抗体检测[J].《中国动物检疫》编辑部,2020,37(10):127-130.

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  • 在线发布日期: 2020-09-29
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