In the article，basic situation of building Foot-and-mouth disease（FMD）free zone of Jilin Province was summarized，and the adopted main measures and achievements during building process by Jilin Animal Health Supervision Institution were also introduced. For the purpose of offering reference and support for other provinces who would build specific disease free zone，related working experiences were summarized from points of high government attention，division of the task，publicity and training，as well as supervision and examination.