为了解云南省丽江市羊小反刍兽疫（PPR）的免疫状况和病毒感染情况，2017—2020年在全市范围内累计采集580个场点的4 002份血清学样品和2 556份病原学样品，分别采用ELISA方法和荧光RT-PCR方法进行抗体检测和病毒核酸检测，并对检测结果进行统计分析。结果显示：2017—2020年丽江市羊PPR个体免疫合格率为76.29%，群体合格率为83.67%；除2020年（69.23%）外，其他年份（75.33%~82.82%）均超过了农业农村部要求的最低合格标准（70%）；种羊场、商品羊场、散养户和屠宰场的个体免疫合格率分别为91.20%、84.51%、76.67%和33.40%，所有样品均未检测到PPR病毒核酸阳性。结果表明：丽江市未在全市范围内形成PPR病原污染，在未引入新疫源的前提下，疫情发生风险较低；但整体的羊群免疫抗体合格率不高，且呈下滑趋势，尤其是散养及屠宰羊群缺乏足够的抗体保护。因此，应继续加强PPR强制免疫和监测，加大羊只引种检疫和调运监管力度，提升该病的整体防控能力。
In order to investigate the status of immunization and pathogenic infection of peste des petits ruminants（PPR）in sheep in Lijiang City of Yunnan Province，4 002 serological samples and 2 556 etiological samples were collected from 580 premises across the City during 2017 to 2020 for detection of antibodies and viral nucleic acids by ELISA and fluorescent RT-PCR respectively，then the test results were summarized and analyzed. The results showed that from 2017 to 2020，the immune qualification rate at individual level was 76.29%，and that at population level was 83.67%，both of which exceeded the minimum standard（70%）required by the Ministry of Agriculture and Rural Affairs in these years（75.33%-82.82%）except in 2020（69.23%）；the immune qualification rates at individual level were 91.20%、84.51%、76.67% and 33.40% in sheep breeding farms，commercial sheep farms，free-range households and slaughterhouses，respectively，no PPR virus nucleic acid was detected in all samples. In conclusion，PPR pathogen contamination had not been distributed across the city，and the risk of occurrence of an outbreak was low provided that no any new source was introduced；but the overall qualification rate was low and tended to decrease，especially free-range sheep and those for slaughtering that lacked of sufficient antibody protection. It was thus necessary to continue to strengthen compulsory immunization against PPR and monitoring，make efforts to supervise the introduction and transportation of sheep and improve the overall capacities for prevention and control of the disease.