我国猪群H1N1亚型流感病毒流行情况与生物学特性
作者:
作者单位:

作者简介:

通讯作者:

中图分类号:

S851.3

基金项目:


Prevalence and Biological Characteristics of Swine Influenza Virus H1N1 Subtype in China
Author:
Affiliation:

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    感染猪群的流感病毒(swine influenza virus,SIV)对养猪业和公共卫生均构成一定威胁。对H1N1亚型SIV监测发现,经典猪H1N1(classical swine H1N1,CS H1N1)、欧亚类禽H1N1(Eurasian avian-like H1N1,EA H1N1)、人源H1N1和2009年大流行H1N1(2009 pandemic H1N1,pdm/09 H1N1)亚型流感病毒均在我国猪群内传播,并且这些SIV相互间不断发生基因重组。一些H1N1亚型SIV会偶发性引起人类感染,对公共卫生存在潜在威胁。此外,H1N1亚型SIV还会引发犬和水貂等动物的感染。经动物模型试验发现,不同H1N1亚型SIV在小鼠、鸡、猪和雪貂中的致病性及传播能力不同,其中一些SIV分离株显示出致死性,需要对其进行生物学特征研究,评估其对人类的潜在风险。SIV导致的猪死亡率不高,因而对其关注较少。但是禽源和哺乳动物源流感病毒可以在猪体内重组为可引起人类大流行的流感病毒毒株,因此应该及时了解SIV的流行情况与生物学特性,并做好相应的控制措施,以减少经济损失,避免具有大流行潜力毒株出现。本文回顾了H1N1亚型SIV的流行情况和生物学特征,以期为控制其流行提供理论依据。

    Abstract:

    In case of any prevalence in pigs,swine influenza virus(SIV)would pose a certain threat to pig industry and public health. It was found that,by epidemiological surveillance on SIV H1N1 subtype,classical swine H1N1(CS H1N1),Eurasian avian-like H1N1(EA H1N1),human-derived H1N1 and 2009 pandemic H1N1(pdm/09 H1N1)subtype influenza virus were prevalent in pigs in China,all of which constantly produced genetic recombination with each others. In addition to infection in dogs,minks and other animals,some H1N1 subtypes of SIVs might episodically infect human,posing their potential threat to public health. In animal model experiment,the pathogenicity and spread ability of different H1N1 subtypes were different in mice,chickens,pigs and ferrets,some of which showed lethality,so it would be important to study their biological characteristics to evaluate any potential risk to human. SIV might lead to low level of mortality in pigs,which was less concerned,but its prevalence and biological characteristics should be timely investigated,followed by relevant control measures to reduce any possible economic loss and to avoid any occurrence of viruses with pandemic potential,as the avian and mammalian influenza viruses could be recombined into influenza virus strains in pigs,which might cause human pandemics. In a word,the prevalence and biological characteristics of SIV H1N1 subtype were reviewed in the paper,with a view to providing a theoretical basis for its control strategies.

    参考文献
    相似文献
    引证文献
引用本文

赵玉仲,桑浩田,肖一红,刘思当,韩乐斌,侯衍猛.我国猪群H1N1亚型流感病毒流行情况与生物学特性[J].《中国动物检疫》编辑部,2023,40(1):35-41.

复制
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期: 2023-01-10
  • 出版日期:
您是第位访问者
《中国动物检疫》编辑部 ® 2023 版权所有
地址:山东省青岛市南京路369号《中国动物检疫》编辑部 邮编:266032
电话:0532-85623545 0532-85622559 0532-85642906 传真:0532-85621826 鲁ICP备08016398号-3
技术支持:北京勤云科技发展有限公司